Cases by Disease Category
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Case No : 1349 Date 2023-08-28
- Courtesy of Kyu Bin Kim / Pusan National University Yangsan Hospital
- Age/Sex 62 / F
- Chief ComplaintMultiple lung nodules
Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Pulmonary amyloidosis (nodular parenchymal type)
- Radiologic Findings
- Fig 1. Chest PA shows
- Mottled calcifications, linear streaky opacities at RULz, suggesting old pulmonary TB.
- Multinodular opacities at bilateral lung (the largest : at right middle lung zone)
Fig 2-6 CT scan reveals
- Well-defined multiple nodules with lobulated margin at bilateral lung.
- Nodules with or without calcification.
- Calcifications with fibrostreaky opacity at RUL apical segment, suggesting old TB.
- Brief Review
- Pulmonary amyloidosis
- Rare manifestation of amyloidosis by involvement of lung parenchyma
There are three patterns of pulmonary amyloidosis.
- Diffuse tracheobronchial amyloidosis
- Nodular parenchymal type
- Diffuse alveolar septal type
Nodular parenchymal type
1. Clinical features
- Benign clinical course with indolent growth over time
2. Image findings
A. Solitary pulmonary mass (amyloidoma)
B. Multiple pulmonary nodules
C. Variable size and margins
- from smooth to spiculated margin
D. Progressive calcification over time
- References
- Sugi et al. Amyloidosis : multisystem spectrum of disease with pathologic correlation
- RadioGraphics 2021; 41:1454 - Keywords
No. of Applicants : 84
- ▶ Correct Answer : 20/84, 23.8%
-
- - Ishikawa Matto Central Hospital , Japan MANABU AKIMOTO
- - Chonnam National University Hwasun Hospital , Korea (South) KWANGKUN CHO
- - , Japan KYOKO NAGAI
- - Shiga University of Medical Science , Japan AKITOSHI INOUE
- - Kyoto City Hospital , Japan YUSUKE UTSUNOMIYA
- - Chonnam National University Hwasun Hospital , Korea (South) DONGHUN HAN
- - Osaka University , Japan AKINORI HATA
- - , Japan HIKARI FUKUI
- - Shimada General Medical Center , Japan HAYATO NOZAWA
- - Soonchunhyang University Hospital Bucheon , Korea (South) HYEJOO PARK
- - , Japan YUKIKO USUI
- - Gifu University Hospital , Japan Yo Kaneko
- - Jichi Medical University, School of Medicine , Japan MITSURU MATSUKI
- - , Japan MIYUKO FUJITA
- - Other , Korea (South) SEONG WON JANG
- - Others , India PURUSHOTHAMA RAO TUMMALA
- - Chonnam National University Hospital , Korea (South) KIM SANG GYUN
- - Chonnam National University Hospital , Korea (South) SEUNG WAN KANG
- - Other , Korea (South) YONG HO JANG
- - , Korea (South) JIN WOO YOON
- ▶ Correct Answer as Differential Diagnosis : 22/84, 26.2%
-
- - ZIGONG TCM HOSPITAL OF CHINA , China CAO CUN YOU
- - Vita Hospital , Brazil DIOGO LAGO PINHEIRO
- - Oita University, Faculty of Medicine , Japan FUMITO OKADA
- - Ajou University Hospital , Korea (South) HAEIN LEE
- - Ajou University Hospital , Korea (South) HYUNSEUNG LEE
- - The University of Tokyo Hospital , Japan TOSHIHIRO FURUTA
- - Narayana Multispeciality Hospital Jaipur Rajasthan , India JAINENDRA JAIN
- - Ajou University Hospital , Korea (South) JAYOUNG MOON
- - Avrasya Hospital/ISTANBUL , Turkey MURAT ULUSOY
- - Osaka metropolitan university Hospital , Japan TATSUSHI OURA
- - Dokkyo Medical University , Japan HIROAKI ARAKAWA
- - Seoul National University Hospital , Korea (South) SUNGHO HONG
- - , Korea (South) KIM HYE IN
- - Yonsei University,Severance Hospital , Korea (South) SEO BUM CHO
- - Chonnam Hospital , Korea (South) JAEHYUN PARK
- - Nerimahikarigaoka hospital , Japan TAKANA HAYASHI
- - Matsunami General Hospital , Japan TARO TAKEDA
- - Chonnam National University Hwasun Hospital , Korea (South) SONG MYUNG WON
- - , Japan NOBUYUKI OTANI
- - The Catholic University of Korea Yoeuido St. Mary , Korea (South) CHAWOONG JEON
- - Kyoto university , Japan AKIHIKO SAKATA
- - Jiangsu province hospital , China WANGJIAN ZHA
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